• selective estrogen receptor modulators Preclinical studies h

  2019-04-19

  

  Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer selective estrogen receptor modulators [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- indu

• LQT can have numerous clinical manifestations ranging

  2019-04-19

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

• March marked annual World TB Day this year s theme

  2019-04-19

  

  March 24 marked annual World TB Day, this year\'s theme being “reach the 3 million” who acquire tuberculosis every year but who do not get diagnosed, treated, or cured. Why do so many patients with this life-threatening infectious disease go under the radar? One reason, as Madhukar Pai and colleague

• br It s that time

  2019-04-19

  

  It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A

• En raz n del desarrollo que la

  2019-04-19

  

  En razón del desarrollo que la oposición entre el individuo y la colectividad ha cobrado en Occidente, y cada vez es más aguda, se han entendido o malentendido las demandas de los pueblos indígenas como contrarias abiraterone acetate los derechos individuales, pero tal perspectiva es reduccionista,

• There are several limitations to the

  2019-04-18

  

  There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int

• Atrial fibrosis is one of

  2019-04-18

  

  Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s

• Para ofrecer una idea del

  2019-04-18

  

  Para ofrecer una idea del carácter de la revista, se analizan los textos que publicó Homero Garza en esa época. En su poesía la brisa tiene arterias, el agua, células, la voz se alimenta de fantasmas, el alma posee corteza, el llanto, piel, el letargo eleva espigas, las palabras tienen dientes de as

• br Reflexionar sobre esta frase que aparece temprano en es

  2019-04-18

  

  Reflexionar sobre esta frase, que aparece temprano en , es vislumbrar una versión concentrada del libro entero. Digo bien una versión, pues se podrían expresar otras dinámicas igualmente representativas de la obra al reemplazar las palabras ‘fijeza’ y ‘cambio’ por ‘destrucción’ y ‘renovación’, ‘de

• Others have observed the marked differences in clinicopathol

  2019-04-18

  

  Others have observed the marked differences in clinicopathological characteristics between breast cancer subtypes by IHC study. However, they reported that triple negative and HER2 patients are at high risk of recurrences after adjusting for age, stage and histological grade. Our data support this o

• br Conclusions br Acknowledgements This work was supported b

  2019-04-18

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• The goals are set the targets laid

  2019-04-18

  

  The goals are set; the targets laid out. The fighting is over. In just over a week\'s time, heads of state worldwide will commit to the , with its 17 Sustainable Development Goals (SDGs) and 169 associated targets. Country representatives will resolve to do everything from ending poverty and hunger

• br Universalismo cosmopolitismo y pol ticas culturales La

  2019-04-18

  

  Universalismo, cosmopolitismo y políticas culturales La conciencia universalista y el cosmopolitismo han sido productos de los movimientos y de los intercambios cada vez más acelerados de nuestro mundo. Desde las expansiones mercantiles y católicas del siglo xvi, los parámetros y los referentes a

• Cryotherapy related soft tissue injury usually occurs within

  2019-04-17

  

  Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection

• This Ca overload activates the

  2019-04-17

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

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