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br Purpose br Methods Participating centers Forty main ICSD
2019-05-09
Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register
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br Discussion Clinically HES may be separated
2019-05-09
Discussion Clinically, HES may be separated into two subgroups: HES with, and HES without gene abnormality such as PDGFRA, PDGFRB, or FGFR1. The standard therapy of HES without gene abnormality is steroid; by contrast, the first-line therapy of HES with gene abnormality is imatinib. Although in-
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RG2833 br Conclusion and future directions br Conflict of in
2019-05-09
Conclusion and future directions Conflict of interest Acknowledgments Introduction Epithelial-mesenchymal transition (EMT) is a process by which epithelial RG2833 lose their polarity and are converted to a mesenchymal phenotype; recently, this has been regarded as the critical event that
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Twenty six of the patients had an early
2019-05-09
Twenty-six of the 98 patients had an early discontinuation due to recurrence: there were 14 patients with distant no donors and 12 with local recurrence. Most distant metastatic events (71.4%) occurred within the initial two years. Of the other 72 patients with early discontinuation of ET, only sev
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Several anti platelet therapies have been evaluated
2019-05-09
Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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br Ocular surface squamous neoplasia OSSN
2019-05-08
Ocular surface squamous neoplasia (OSSN) has emerged as an important manifestation of the HIV epidemic, especially in sub-Saharan Africa. This region has not only gained the unenviable position of having the highest prevalence of OSSN, but patients with HIV tend to present with larger tumours and
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Cardiac troponin I cTnI is a well established sensitive
2019-05-08
Cardiac troponin I (cTnI) is a well-established, sensitive, and specific marker of myocardial injury. However, evidence indicates that unrecognized myocardial injury may be occurring with certain conditions such as sepsis without acute coronary ischemic event, which demonstrate elevated cTnI levels.
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br Conclusion Our findings may help physicians in selecting
2019-05-08
Conclusion Our findings may help physicians in selecting high-priority patients for bisphosphonate treatment. Zoledronic MLN4924 is indicated for treating patients with MBD from any malignancy [1,35]; however, many patients do not receive treatment (especially in NSCLC and CRPC). Although it may
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Well designed operational research is needed to refine this
2019-05-08
Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom
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La expansi n exportadora de Argentina hacia
2019-05-08
La expansión exportadora de Argentina hacia Colombia, Perú y Venezuela respondió Etonogestrel distintas razones, pero los mercados obviamente tuvieron mucho que ver. No fue casual que Colombia, por ejemplo, concentrara más de 65% de sus importaciones de Argentina en bienes primarios, pues la agricul
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br Discussion Chronic myelogenous leukemia CML
2019-05-08
Discussion Chronic myelogenous leukemia (CML) is a clonal disorder involving the pluripotent stem cell and is consistently associated with the BCR-ABL1 fusion gene located on the Philadelphia chromosome [1]. The disease typically evolves in 3 distinct clinical stages: chronic and accelerated phas
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Leong et al reported a similar
2019-05-08
Leong et al. reported a similar case of a short circuit in the Riata 1570 defibrillator lead, which manifested as unsuccessful defibrillation [10]. In this case, product analysis of generator indicated structural device damage owing to a short circuit in the defibrillation lead. Marenco et al. also
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ER provides the clinician with
2019-05-08
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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La expedici n colombiana de Preuss fue patrocinada por
2019-05-07
La expedición colombiana de Preuss fue patrocinada por la fundación que Joseph Florimont, duque de Loubat, había establecido para la Cátedra de Lingüística, Arqueología y Etnología Americanas. Igual que la Expedición al Nayarit (1905-1907), el viaje igf1r inhibitor Colombia (1913-1919) combina objet
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Demand for kidney transplantation for ESKD has already outst
2019-05-07
Demand for kidney transplantation for ESKD has already outstripped the supply of donated multidrug resistance transporter from living donors, notwithstanding the inadequate donor pool. End-of-life donation can potentially expand the donor pool but is less common. For example, in India, among the 12
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