• Introduction Several types of cancers including those

  2019-06-28

  

  Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s

• Numerous animal studies have demonstrated beyond doubt that

  2019-06-28

  

  Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit

• Despite a substantial reduction in global maternal deaths

  2019-06-28

  

  Despite a substantial reduction in global maternal deaths due to postpartum haemorrhage between 1990 and 2013 (from 71 295 to 44 190), this condition continues to be the main cause of maternal mortality worldwide. In sub-Saharan Africa and south Asia, many women still deliver at home without a skill

• Education is part of the foundation for

  2019-06-28

  

  Education is part of the foundation for a successful ASP. A well-designed educational program provides prescribers with updated knowledge on antimicrobial use, drug resistance, and infectious disease management. Educational interventions have been shown to improve prescribing competency, change pres

• The main products of EBM are evidence based guidelines

  2019-06-28

  

  The main products of EBM are evidence-based guidelines (EBGs), “systematically developed statements to assist practitioner and patient decision about appropriate health care for specific clinical circumstances” [21]. EBGs indeed substantially improve clinical care [29]. Preliminary steps for guidel

• br Material and methods br Results

  2019-06-28

  

  Material and methods Results Discussion The present study found that the plasma BNP level was higher in patients with LAA thrombus than in those without LAA thrombus. Additionally, the BNP level was negatively associated with peak LAA velocity evaluated using TEE and positively associated w

• Vollmer and colleagues distinctive multilevel modelling has

  2019-06-28

  

  Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau

• br Methods This prospective study was conducted at

  2019-06-27

  

  Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befo

• Severe ECG abnormality associated with systolic dysfunction

  2019-06-27

  

  Severe ECG abnormality associated with systolic dysfunction of our DM1 patients. Some degree of electro-mechanical correlation has been demonstrated in several previous studies on DM1 subjects. DM1 patients with prolonged PR or QRS intervals are at four-times higher risk to develop LV systolic dysfu

• The outcome of sinus node modification with radiofrequency a

  2019-06-27

  

  The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system

• En El fistol del diablo Payno construye

  2019-06-27

  

  En El fistol del diablo Payno construye un argumento o trama que abriga una rencilla entre naciones que se remonta Iloperidone la guerra de Texas, con memoria de El Alamo y la batalla de San Jacinto en la que el general Santa Anna es sorprendido y vencido por Sam Houston. La historia se repite, por

• As condi es desta reinser o

  2019-06-27

  

  As condições desta “reinserção” seriam consolidadas Fmoc-Lys(Dnp)-OH weight partir do chamado “autogolpe”, quando Fujimori fechou o congresso e interveio no poder judicial em abril de 1992, decretando à moda argentina um “Gobierno de emergencia y reconstrucción nacional”. Em uma perversão da democra

• Al mismo tiempo que el joven no cree en la

  2019-06-27

  

  Al mismo tiempo que el joven no cree en la matanza, actualiza antiguos estereotipos reforzados por imágenes que construyen el imaginario social. ¿Qué otra cosa hace Altunaga, sino problematizar la axiología revolucionaria del fin del racismo cuando pone en boca del barrendero la siguiente reflexión?

• br Efforts to address malnutrition

  2019-06-27

  

  Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man

• Introduction Brugada syndrome is severe

  2019-06-27

  

  Introduction Brugada syndrome is severe arrhythmia characterized by specific ST elevations in precordial leads and sudden ventricular fibrillation (VF), and the condition may result in sudden cardiac death [1–5]. By implanting defibrillation devices, also known as implantable cardioverter-defibrill

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